Volume 3, Issue 4 (3-2017)                   nbr 2017, 3(4): 279-287 | Back to browse issues page


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Kaboli Kafshgiri S, Parivar K, Baharara J, Hayati Roodbari N, Kerachian M A. Comparison the effect of movento, a chemical pesticide, with chitosan, a biologic pesticide, on female reproductive system in Balb/C mice . nbr. 2017; 3 (4) :279-287
URL: http://nbr.khu.ac.ir/article-1-2789-en.html
Abstract:   (2661 Views)

Chemical pesticides possess toxic and destructive impacts on the reproductive system and disrupt endocrine function. In this experimental study, the effect of movento, as a chemical pesticide, was investigated in comparison with chitosan, a biological pesticide, on the female reproductive system in vivo. In this study, 56 mice were randomly dived into 7 groups including control and experimental groups treated with movento and chitosan. After a 21-day treatment, mice were killed and their ovaries and blood being collected. In addition, the samples were fixed and stained with H & E method. The results exhibited that treatment with 2.5 and 5 mg/kg chitosan had no significant effect on the number and diameter of primary, secondary and antral follicles, while these items were significantly reduced in 10 mg/kg ch-itosan group and all movento-treated groups as well. In addition, the level of sexual hormones, such as estradiol, FSH and LH, was decreased in 10 mg/kg chitosan group and all movento-treated groups in comparison with the control gr-oup. The findings showed that movento affected the sexual hormone levels, ovary and ovarian follicle structure and in-duced abnormality in female reproductive system, while chitosan, as a biological pesticide, should be used due to its minimum effects on female reproductive system

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Type of Study: Original Article | Subject: Plant Biology
Received: 2017/03/13 | Revised: 2017/03/16 | Accepted: 2017/03/13 | Published: 2017/03/13 | ePublished: 2017/03/13

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