Aoki I. Entropy flow and entropy production in the human body in basal conditions. J Theor Biol. 1989 Nov 8;141(1):11-21. doi: 10.1016/s0022-5193(89)80004-9. PMID: 2634157.
McFarland J, Wenderoth MP, Michael J, Cliff W, Wright A, Modell H. A conceptual framework for homeostasis: development and validation. Adv Physiol Educ. 2016 Jun;40(2):213-22. doi: 10.1152/advan.00103.2015. PMID: 27105740; PMCID: PMC5002438.
McEwen BS. Neurobiological and Systemic Effects of Chronic Stress. Chronic Stress (Thousand Oaks). 2017 Jan-Dec;1:2470547017692328. doi: 10.1177/2470547017692328. Epub 2017 Apr 10. PMID: 28856337; PMCID: PMC5573220.
Sennesh E, Theriault J, Brooks D, van de Meent JW, Barrett LF, Quigley KS. Interoception as modeling, allostasis as control. Biol Psychol. 2022 Jan;167:108242. doi: 10.1016/j.biopsycho.2021.108242. Epub 2021 Dec 20. PMID: 34942287; PMCID: PMC9270659.
McEwen BS. Physiology and neurobiology of stress and adaptation: central role of the brain. Physiol Rev. 2007 Jul;87(3):873-904. doi: 10.1152/physrev.00041.2006. PMID: 17615391.
Kleckner IR, Zhang J, Touroutoglou A, Chanes L, Xia C, Simmons WK, Quigley KS, Dickerson BC, Barrett LF. Evidence for a Large-Scale Brain System Supporting Allostasis and Interoception in Humans. Nat Hum Behav. 2017;1:0069. doi: 10.1038/s41562-017-0069. Epub 2017 Apr 24. PMID: 28983518; PMCID: PMC5624222.
Laureys S, Schiff ND. Coma and consciousness: paradigms (re)framed by neuroimaging. Neuroimage. 2012 Jun;61(2):478-91. doi: 10.1016/j.neuroimage.2011.12.041. Epub 2011 Dec 27. PMID: 22227888.
Edlow BL, Claassen J, Schiff ND, Greer DM. Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies. Nat Rev Neurol. 2021 Mar;17(3):135-156. doi: 10.1038/s41582-020-00428-x. Epub 2020 Dec 14. PMID: 33318675; PMCID: PMC7734616.
Carhart-Harris RL, Goodwin GM. The Therapeutic Potential of Psychedelic Drugs: Past, Present, and Future. Neuropsychopharmacology. 2017 Oct;42(11):2105-2113. doi: 10.1038/npp.2017.84. Epub 2017 Apr 26. PMID: 28443617; PMCID: PMC5603818.
Zhao X, Du Y, Yao Y, Dai W, Yin Y, Wang G, Li Y, Zhang L. Psilocybin promotes neuroplasticity and induces rapid and sustained antidepressant-like effects in mice. J Psychopharmacol. 2024 May;38(5):489-499. doi: 10.1177/02698811241249436. Epub 2024 Apr 28. PMID: 38680011.
Ly C, Greb AC, Cameron LP, Wong JM, Barragan EV, Wilson PC, Burbach KF, Soltanzadeh Zarandi S, Sood A, Paddy MR, Duim WC, Dennis MY, McAllister AK, Ori-McKenney KM, Gray JA, Olson DE. Psychedelics Promote Structural and Functional Neural Plasticity. Cell Rep. 2018 Jun 12;23(11):3170-3182. doi: 10.1016/j.celrep.2018.05.022. PMID: 29898390; PMCID: PMC6082376.
de Vos CMH, Mason NL, Kuypers KPC. Psychedelics and Neuroplasticity: A Systematic Review Unraveling the Biological Underpinnings of Psychedelics. Front Psychiatry. 2021 Sep 10;12:724606. doi: 10.3389/fpsyt.2021.724606. PMID: 34566723; PMCID: PMC8461007.
Carhart-Harris RL, Erritzoe D, Williams T, Stone JM, Reed LJ, Colasanti A, Tyacke RJ, Leech R, Malizia AL, Murphy K, Hobden P, Evans J, Feilding A, Wise RG, Nutt DJ. Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin. Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):2138-43. doi: 10.1073/pnas.1119598109. Epub 2012 Jan 23. PMID: 22308440; PMCID: PMC3277566.
Smausz R, Neill J, Gigg J. Neural mechanisms underlying psilocybin's therapeutic potential - the need for preclinical in vivo electrophysiology. J Psychopharmacol. 2022 Jul;36(7):781-793. doi: 10.1177/02698811221092508. Epub 2022 May 30. PMID: 35638159; PMCID: PMC9247433.
Flanagan TW, Nichols CD. Psychedelics as anti-inflammatory agents. Int Rev Psychiatry. 2018 Aug;30(4):363-375. doi: 10.1080/09540261.2018.1481827. Epub 2018 Aug 13. PMID: 30102081.
Koseli E, Buzzi B, Honaker T, Rakholia Y, Lewis M, Gaines-Smith M, Jaster AM, Gonzalez-Maeso J, Damaj MI. IUPHAR Article: Psilocybin induces long-lasting effects via 5-HT2A receptors in mouse models of chronic pain. Pharmacol Res. 2025 May;215:107699. doi: 10.1016/j.phrs.2025.107699. Epub 2025 Mar 17. PMID: 40107634; PMCID: PMC12107474.
Zanikov T, Gerasymchuk M, Ghasemi Gojani E, Robinson GI, Asghari S, Groves A, Haselhorst L, Nandakumar S, Stahl C, Cameron M, Li D, Rodriguez-Juarez R, Snelling A, Hudson D, Fiselier A, Kovalchuk O, Kovalchuk I. The Effect of Combined Treatment of Psilocybin and Eugenol on Lipopolysaccharide-Induced Brain Inflammation in Mice. Molecules. 2023 Mar 14;28(6):2624. doi: 10.3390/molecules28062624. PMID: 36985596; PMCID: PMC10056123.
Carhart-Harris RL, Leech R, Hellyer PJ, Shanahan M, Feilding A, Tagliazucchi E, Chialvo DR, Nutt D. The entropic brain: a theory of conscious states informed by neuroimaging research with psychedelic drugs. Front Hum Neurosci. 2014 Feb 3;8:20. doi: 10.3389/fnhum.2014.00020. PMID: 24550805; PMCID: PMC3909994.
Tagliazucchi E, Roseman L, Kaelen M, Orban C, Muthukumaraswamy SD, Murphy K, Laufs H, Leech R, McGonigle J, Crossley N, Bullmore E, Williams T, Bolstridge M, Feilding A, Nutt DJ, Carhart-Harris R. Increased Global Functional Connectivity Correlates with LSD-Induced Ego Dissolution. Curr Biol. 2016 Apr 25;26(8):1043-50. doi: 10.1016/j.cub.2016.02.010. Epub 2016 Apr 13. PMID: 27085214.
Doss MK, Považan M, Rosenberg MD, Sepeda ND, Davis AK, Finan PH, Smith GS, Pekar JJ, Barker PB, Griffiths RR, Barrett FS. Psilocybin therapy increases cognitive and neural flexibility in patients with major depressive disorder. Transl Psychiatry. 2021 Nov 8;11(1):574. doi: 10.1038/s41398-021-01706-y. PMID: 34750350; PMCID: PMC8575795.
Szpręgiel I, Bysiek A. Psilocybin and the glutamatergic pathway: implications for the treatment of neuropsychiatric diseases. Pharmacol Rep. 2024 Dec;76(6):1297-1304. doi: 10.1007/s43440-024-00660-y. Epub 2024 Oct 16. PMID: 39412581; PMCID: PMC11582295.
Shafiee A, Arabzadeh Bahri R, Rafiei MA, Esmaeilpur Abianeh F, Razmara P, Jafarabady K, Amini MJ. The effect of psychedelics on the level of brain-derived neurotrophic factor: A systematic review and meta-analysis. J Psychopharmacol. 2024 May;38(5):425-431. doi: 10.1177/02698811241234247. Epub 2024 Feb 22. Retraction in: J Psychopharmacol. 2025 May 15:2698811251341228. doi: 10.1177/02698811251341228. PMID: 38385351.
Nagahara AH, Tuszynski MH. Potential therapeutic uses of BDNF in neurological and psychiatric disorders. Nat Rev Drug Discov. 2011 Mar;10(3):209-19. doi: 10.1038/nrd3366. PMID: 21358740.
Park H, Poo MM. Neurotrophin regulation of neural circuit development and function. Nat Rev Neurosci. 2013 Jan;14(1):7-23. doi: 10.1038/nrn3379. PMID: 23254191.
De Gregorio D, Aguilar-Valles A, Preller KH, Heifets BD, Hibicke M, Mitchell J, Gobbi G. Hallucinogens in Mental Health: Preclinical and Clinical Studies on LSD, Psilocybin, MDMA, and Ketamine. J Neurosci. 2021 Feb 3;41(5):891-900. doi: 10.1523/JNEUROSCI.1659-20.2020. Epub 2020 Nov 30. PMID: 33257322; PMCID: PMC7880300.
Carhart-Harris RL, Nutt DJ. Serotonin and brain function: a tale of two receptors. J Psychopharmacol. 2017 Sep;31(9):1091-1120. doi: 10.1177/0269881117725915. Epub 2017 Aug 31. PMID: 28858536; PMCID: PMC5606297.
Vargas MV, Dunlap LE, Dong C, Carter SJ, Tombari RJ, Jami SA, Cameron LP, Patel SD, Hennessey JJ, Saeger HN, McCorvy JD, Gray JA, Tian L, Olson DE. Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors. Science. 2023 Feb 17;379(6633):700-706. doi: 10.1126/science.adf0435. Epub 2023 Feb 16. PMID: 36795823; PMCID: PMC10108900.
Flood JF, Cherkin A. Fluoxetine enhances memory processing in mice. Psychopharmacology (Berl). 1987;93(1):36-43. doi: 10.1007/BF02439584. PMID: 3114813.
Popova D, Castrén E, Taira T. Chronic fluoxetine administration enhances synaptic plasticity and increases functional dynamics in hippocampal CA3-CA1 synapses. Neuropharmacology. 2017 Nov;126:250-256. doi: 10.1016/j.neuropharm.2017.09.003. Epub 2017 Sep 6. PMID: 28887184.
Dai JX, Han HL, Tian M, Cao J, Xiu JB, Song NN, Huang Y, Xu TL, Ding YQ, Xu L. Enhanced contextual fear memory in central serotonin-deficient mice. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11981-6. doi: 10.1073/pnas.0801329105. Epub 2008 Aug 11. PMID: 18695238; PMCID: PMC2575315.
Fonseca MS, Murakami M, Mainen ZF. Activation of dorsal raphe serotonergic neurons promotes waiting but is not reinforcing. Curr Biol. 2015 Feb 2;25(3):306-315. doi: 10.1016/j.cub.2014.12.002. Epub 2015 Jan 15. PMID: 25601545.
Sarnyai Z, Sibille EL, Pavlides C, Fenster RJ, McEwen BS, Toth M. Impaired hippocampal-dependent learning and functional abnormalities in the hippocampus in mice lacking serotonin(1A) receptors. Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14731-6. doi: 10.1073/pnas.97.26.14731. PMID: 11121072; PMCID: PMC18987.
Koenig J, Cosquer B, Cassel JC. Activation of septal 5-HT1A receptors alters spatial memory encoding, interferes with consolidation, but does not affect retrieval in rats subjected to a water-maze task. Hippocampus. 2008;18(1):99-118. doi: 10.1002/hipo.20368. PMID: 17924524.
King AR, Martin IL, Seymour KA. Reversal learning facilitated by a single injection of lysergic acid diethylamide (LSD 25) in the rat. Br J Pharmacol. 1972 May;45(1):161P-162P. PMID: 5041478; PMCID: PMC1666253.
King AR, Martin IL, Melville KA. Reversal learning enhanced by lysergic acid diethylamide (LSD): concomitant rise in brain 5-hydroxytryptamine levels. Br J Pharmacol. 1974 Nov;52(3):419-26. doi: 10.1111/j.1476-5381.1974.tb08611.x. PMID: 4458849; PMCID: PMC1777004.
Torrado Pacheco A, Olson RJ, Garza G, Moghaddam B. Acute psilocybin enhances cognitive flexibility in rats. bioRxiv [Preprint]. 2023 Jan 9:2023.01.09.523291. doi: 10.1101/2023.01.09.523291. Update in: Neuropsychopharmacology. 2023 Jun;48(7):1011-1020. doi: 10.1038/s41386-023-01545-z. PMID: 36712091; PMCID: PMC9881983.
van Praag H, Schinder AF, Christie BR, Toni N, Palmer TD, Gage FH. Functional neurogenesis in the adult hippocampus. Nature. 2002 Feb 28;415(6875):1030-4. doi: 10.1038/4151030a. PMID: 11875571; PMCID: PMC9284568.
van Praag, H., Kempermann, G., & Gage, F. H. (1999). Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus.
Nature Neuroscience, 2(3), 266–270.
https://doi.org/10.1038/6368
Nilsson M, Perfilieva E, Johansson U, Orwar O, Eriksson PS. Enriched environment increases neurogenesis in the adult rat dentate gyrus and improves spatial memory. J Neurobiol. 1999 Jun 15;39(4):569-78. doi: 10.1002/(sici)1097-4695(19990615)39:4<569::aid-neu10>3.0.co;2-f. PMID: 10380078.
Shors TJ, Miesegaes G, Beylin A, Zhao M, Rydel T, Gould E. Neurogenesis in the adult is involved in the formation of trace memories. Nature. 2001 Mar 15;410(6826):372-6. doi: 10.1038/35066584. Erratum in: Nature 2001 Dec 20-27;414(6866):938. PMID: 11268214.
Shors TJ, Townsend DA, Zhao M, Kozorovitskiy Y, Gould E. Neurogenesis may relate to some but not all types of hippocampal-dependent learning. Hippocampus. 2002;12(5):578-84. doi: 10.1002/hipo.10103. PMID: 12440573; PMCID: PMC3289536.
Catlow BJ, Song S, Paredes DA, Kirstein CL, Sanchez-Ramos J. Effects of psilocybin on hippocampal neurogenesis and extinction of trace fear conditioning. Exp Brain Res. 2013 Aug;228(4):481-91. doi: 10.1007/s00221-013-3579-0. Epub 2013 Jun 2. PMID: 23727882.
Fölsz O, Trouche S, Croset V. Adult-born neurons add flexibility to hippocampal memories. Front Neurosci. 2023 Feb 15;17:1128623. doi: 10.3389/fnins.2023.1128623. PMID: 36875670; PMCID: PMC9975346.
Alenina N, Klempin F. The role of serotonin in adult hippocampal neurogenesis. Behav Brain Res. 2015 Jan 15;277:49-57. doi: 10.1016/j.bbr.2014.07.038. Epub 2014 Aug 11. PMID: 25125239.
Shao LX, Liao C, Gregg I, Davoudian PA, Savalia NK, Delagarza K, Kwan AC. Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo. Neuron. 2021 Aug 18;109(16):2535-2544.e4. doi: 10.1016/j.neuron.2021.06.008. Epub 2021 Jul 5. PMID: 34228959; PMCID: PMC8376772.
LX, Liao C, Gregg I, Davoudian PA, Savalia NK, Delagarza K, Kwan AC. Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo. Neuron. 2021 Aug 18;109(16):2535-2544.e4. doi: 10.1016/j.neuron.2021.06.008. Epub 2021 Jul 5. PMID: 34228959; PMCID: PMC8376772.
